Webinar
Human Dorsal Root Ganglia Studies on Ectopic Spontaneous Activity

Explore the complex mechanisms behind cancer-related neuropathic pain in this insightful webinar led by Dr. Patrick Dougherty, Professor of Pain Medicine at the University of Texas M.D. Anderson Cancer Center. With over two decades of experience, Dr. Dougherty shares his how ectopic discharge activity from primary afferent neurons contributes to spontaneous pain—and how innate immune mechanisms may drive this process.

Through a unique combination of human psychophysical studies and animal model research, Dr. Dougherty’s work sheds light on the peripheral and central changes caused by cancer and its treatments. Learn how his team is using human dorsal root ganglia (DRG) tissue to uncover the sensory pathways involved, while also investigating potential neuroprotective therapies.
This on-demand session offers a deep dive into the pathophysiology of neuropathic pain and the future of pain management for cancer patients.

Speaker

Dr. Patrick M Dougherty, PhD, of MD Anderson Cancer Center
Professor, Department of Pain Medicine-Research
The University of Texas MD Anderson Cancer Center
Associate Professor, Department of Neurobiology & Anatomy
The University of Texas Health Science Center at Houston

Dr. Patrick M. Dougherty is a neuroscientist and Professor in the Department of Pain Medicine-Research at The University of Texas MD Anderson Cancer Center, with a joint appointment as Associate Professor in the Department of Neurobiology & Anatomy at The University of Texas Health Science Center at Houston. With over two decades of experience, Dr. Dougherty’s research focuses on the neurobiological mechanisms underlying neuropathic pain, particularly in the context of cancer and its treatment.

His work combines psychophysical studies in patients with advanced preclinical models to investigate how cancer and chemotherapy alter neural signaling pathways. Dr. Dougherty is recognized for his investigations into ectopic activity in sensory neurons and the role of immune signaling in cancer-related pain. His translational research aims to identify novel targets for pain management and improve the quality of life for patients affected by chronic and treatment-induced neuropathies.

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