In this application note, we show how 28bio CNS-3D Brain Organoids enable high-throughput assessment of AAV transduction, expression dynamics, functional impact, and viability in a single model.

This application note shows how 28bio CNS-3D Organoids and Curi Bio Nautilai and support scalable functional profiling of compounds, including temporal response characterization and repeated-dosing analyses.

Chemotherapy-induced peripheral neuropathy (CIPN) s a significant adverse effect associated with chemotherapy, impacting approximately 68% of cancer patients...

Drug development for central nervous system (CNS) disorders faces a 94.1% failure rate1 in human clinical trials - one of the highest in life sciences. This results in $74B2 spent annually on failed drug candidates throughout the neurological drug development...

CNS-3D technology provides a robust and scalable means for modeling CDKL5 Deficiency Disorder, capturing disease-related phenotypes and enabling high-throughput drug screening.