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Application Notes
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Protocols
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Scientific Posters
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Protocol
6/5/2025
CNS-3D Organoids 96-Well Plate
Protocol
6/5/2025
CNS-3D Organoids 384-Well Plate
Protocol
6/5/2025
CNS-3D Organoids FLIPR Assay
Product Sheet
6/5/2025
CNS-3D Organoids
Product Sheet
6/5/2025
PNS-3D Organoid Services
Application Note
6/5/2025
Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity
Application Note
6/5/2025
Disease Modeling in CNS-3D Technology for High-Throughput Efficacy Assessment of Rescue Therapeutics
Application Note
6/5/2025
Modeling CDKL5 Deficiency Disorder with CNS-3D Organoids for Streamlined Target Discovery
Scientific Poster
5/13/2025
Improving the Stability and Reproducibility of Clinical Neurotoxicity Predictions from a High-throughput Compatible Neural Organoid Platform
Scientific Poster
3/16/2025
Comparison of a 3D Nerve-on-a-Chip Peripheral Nerve Model to 2D Neuronal Assays for Clinical Translation with Antibody Drug Conjugate (ADC) Toxicity Screening
Webinar
10/8/2024
Translating Neurological Stem Cell Research into Therapies for Today's Patients
Scientific Poster
10/5/2024
Onset of CIPN Delayed Through SARM1 Inhibition in Human NerveSim Preclinical Drug Discovery Platform
Scientific Poster
10/5/2024
Clinically Related Rare Neurodevelopmental Disorders Display Distinct Functional Phenotypes in Human iPSC-derived Cortical Organoids
Scientific Poster
6/10/2024
Identification of a Potential Therapeutic Compound for Rett Syndrome Using a Highly Homogenous Human iPSC-derived Cortical Organoid Screening Platform
Scientific Poster
3/10/2024
High-throughput Functional and Morphological Neurotoxicity Screening in Human NerveSim
Publication
6/29/2023
Comparative Assessment of Ca²⁺ Oscillations in 2- and 3-Dimensional hiPSC-Derived and Isolated Cortical Neuronal Networks
Publication
10/18/2022
Assessment of a 3D Neural Spheroid Model to Detect Pharmaceutical-Induced Neurotoxicity
Publication
6/27/2022
A Multiparametric Calcium Signal Screening Platform Using iPSC-Derived Cortical Neural Spheroids
Publication
10/22/2020
Screening for Modulators of Neural Network Activity in 3D Human iPSC-Derived Cortical Spheroids
Scientific Poster
5/7/2020
Modeling Chemotherapy-induced Peripheral Neuropathy using a Nerve-on-a-Chip Microphysiological System
Publication
1/1/2019
Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures
Webinar
Predicting Clinical Neurotoxicity Using Functional Organoids
Webinar
Neurological Drug Discovery and Toxicology Screening
Webinar
Human Schwann Cells: Importance for Peripheral Neuropathy Preclinical Research
Webinar
Human Dorsal Root Ganglia Studies on Ectopic Spontaneous Activity
Webinar
Functional Organoids and their Applications for Disease Modeling
Webinar
ADCs and Peripheral Neuropathy: The Need for New, Predictive Assays
Webinar
Accelerating Care & Research for Neurological Diseases
Webinar
A Case Study on Chemotherapeutic Drug-induced Peripheral Neuropathy
Scientific Poster
Novel Neurotoxicity Screening Platform to Examine Functional Changes in Rodent Dorsal Root Ganglia and Human iPSC-derived Sensory Neuron Cultures
Scientific Poster
Nerve-On-A-Chip for Modelling Motor Neuron Diseases and Preclinical Neurotoxicity Testing
Scientific Poster
Glial Cell Type Composition in a 3D Model of the Central Nervous System
Scientific Poster
Evaluating Human Nerve Conduction Velocity In Vitro as a Novel Metric for Assessing Chemotherapeutics-induced Peripheral Neuropathy
Scientific Poster
Development of Rat DRG Model for Predicting Peripheral Neuroinflammation and Neurotoxicity of Therapeutic Agents
Scientific Poster
Development of an In Vitro Human-derived 3D Model of Dorsal Horn Pain Signaling
Scientific Poster
Development of a High-Content Human Co-culture Model to Investigate Chemotherapy-Induced Peripheral Neuropathy
Scientific Poster
Assessing Chemotherapeutics Neurotoxicity Using Human Cells Based High-Throughput Neuronal-Schwann Cells Culture System
Scientific Poster
An Engineered 3D Peripheral Human "Nerve-on-a-Chip": A Novel Assessment for Neurotoxicity In Vitro
Scientific Poster
A Robust, High-throughput Electrophysiology Platform for Drug Screening in a Peripheral Nerve-on-a-Chip Microphysiological System
Scientific Poster
A Novel, High-throughput Electrophysiology Platform for Compound Screening with a Peripheral Nerve Microphysiological System
Scientific Poster
A Nondestructive, Image-based Cytotoxicity Assessment for Combined Safety and Efficacy Screening in Human-iPSC Derived Organoids
Scientific Poster
A Model for High-throughput Therapeutic Screening of Peripheral Neuropathy in a Human 3D Nerve-on-a-Chip Microphysiological System
Scientific Poster
A High-throughput Electrophysiology Platform for Compound screening with a Peripheral Nerve Microphysiological System
Scientific Poster
A 3D Human Model for Preclinical Drug Screening using a Myelinated Nerve-on-a-Chip Micro-physiological System
Scientific Poster
3D Nerve-on-a-Chip Model Effectively Screens Neurotoxic Compounds
Scientific Poster
Application of a Dual Human Cell System to Measure Potential Off-target Induced Peripheral Neuropathy (PN) for Antibody Drug Conjugate (ADC) candidates and Other Developing Chemotherapeutics
Publication
Microengineered Peripheral Nerve-on-a-chip for Preclinical Physiological Testing
Publication
A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity
Publication
Rotenone Exerts Developmental Neurotoxicity in a Human Brain Spheroid Model
Publication
Engineering a 3D functional human peripheral nerve in vitro using the Nerve-on-a-Chip platform
Publication
Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
Publication
Altered Network and Rescue of Human Neurons Derived from Individuals with Early-Onset Genetic Epilepsy
Publication
Advances in 3D Neuronal Microphysiological Systems: Towards a Functional Nervous System on a Chip
Publication
Modeling Chemotherapy-Induced Peripheral Neuropathy Using a Nerve-on-a-Chip Microphysiological System
Publication
Fabrication and Characterization of 3D Printed, 3D Microelectrode Arrays for Interfacing with a Peripheral Nerve-on-a-Chip