PNS-3D incorporates human sensory neurons and Schwann cells in a 3D microenvironment with embedded electrode arrays, forming 10 mm-long myelinated nerve fibers. Longitudinal electrophysiology and morphology endpoints support characterization of peripheral nerve dysfunction and neuroprotective effects over time.

PNS-3D Services provide human-relevant insights into peripheral nerve safety and drug efficacy across therapeutic modalities, including small molecules and antibody-drug conjugates. Studies can be tailored to your program stage, research question, and decision criteria, from early safety profiling to neuroprotection efficacy testing and custom peripheral nerve workflows.