CNS-3D Inflammatory Organoids are human iPSC-derived cortical organoids containing neurons, astrocytes, and microglia for studies of neuroinflammation, Alzheimer’s disease, and drug efficacy. This immunocompetent 3D brain model enables assessment of inflammation-driven changes in neural function, microglial activation, cytokine release, and tissue-level responses in a human cellular context.

Functional calcium imaging can be combined with complementary endpoints spanning imaging, cytokine analysis, and molecular profiling to support comprehensive insights into neuroinflammatory biology. CNS-3D Inflammatory Organoids are available as assay-ready products for in-house workflows or through CNS Services for end-to-end study design, execution, and analysis.