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Comparison of a 3D Nerve-on-a-Chip Peripheral Nerve Model to 2D Neuronal Assays for Clinical Translation with Antibody Drug Conjugate (ADC) Toxicity Screening
Discover how PNS-3D Organoids improve chemotherapy-induced peripheral neuropathy (CIPN) detection.
Clinically Related Rare Neurodevelopmental Disorders Display Distinct Functional Phenotypes in Human iPSC-derived Cortical Organoids
iPSC-derived cortical organoids for high-throughput drug screening in Rett syndrome and CDKL5 deficiency disorder (CDD).
Assessing Chemotherapeutics Neurotoxicity Using Human Cells Based High-Throughput Neuronal-Schwann Cells Culture System
Learn how AxoSim's 2D monoculture and co-culture models enhance neurotoxicity screening for chemotherapeutics, improving drug safety assessments with human-relevant data.
An Engineered 3D Peripheral Human "Nerve-on-a-Chip": A Novel Assessment for Neurotoxicity In Vitro
Learn how this iPSC-derived model replicates peripheral nerve anatomy to improve drug development insights.
A Robust, High-throughput Electrophysiology Platform for Drug Screening in a Peripheral Nerve-on-a-Chip Microphysiological System
High-content electrophysiological readouts for drug screening applications.
A Novel, High-throughput Electrophysiology Platform for Compound Screening with a Peripheral Nerve Microphysiological System
Discover how electrophysiology-based assessments improve drug development for neuroprotection and neuropathy research.
A Nondestructive, Image-based Cytotoxicity Assessment for Combined Safety and Efficacy Screening in Human-iPSC Derived Organoids
Discover how this nondestructive method improves drug screening by combining safety and efficacy assessments.
A Model for High-throughput Therapeutic Screening of Peripheral Neuropathy in a Human 3D Nerve-on-a-Chip Microphysiological System
Explore NerveSim®, a 3D nerve-on-a-chip microphysiological system for high-throughput screening of peripheral neuropathy. Discover its capabilities in neurotoxicity, neuroprotection, and electrophysiology-based drug development.
A High-throughput Electrophysiology Platform for Compound screening with a Peripheral Nerve Microphysiological System
A 3D peripheral nerve model enabling high-throughput electrophysiology for drug screening, neurotoxicity assessment, and neuroprotection research with clinically relevant insights.